Stem cell therapy as a potential treatment for breast cancer
Xuanqi Song Glossary Aromatase inhibitor, Astrocyte, Blastocyst, Chemotherapy, Ectoderm, Endoderm, Hematopoetic, Immunotherapy, in vitro, Lymphoma, Mesenchymal, Mesoderm, Molecular marker, Mutation, Pluripotent, Pluripotent, Quiescence, Somatic cell, Stem cell therapy Abbreviations Ais, Aromatase inhibitors; ASC, adult stem cell; CSC, cancer stem cell; ESC, embryonic stem cell; HER2, Human epidermal growth factor receptor 2; HR+, hormone receptor positive; […]
Prostate cancer research: Latest advances
Tala Elremmash Glossary: Brachytherapy, BRCA genes, Digital Rectal Examination (DRE), External Beam Radiation Therapy (EBRT), ExoDx Prostate (EPI), 68Ga-PSMA-11, Gleason Score, High Intensity Focused Ultrasound (HIFU), Intensity Modulated Radiation Therapy (IMRT), 4Kscore Test, Multiparametric Magnetic Resonance Imaging (mpMRI), PCA3, Prostatic Intraepithelial Neoplasia (PIN), Prostate-Specific Antigen (PSA), Prostate-specific Membrane Antigen Positron Emission Tomography (PSMA-PET), Stereotactic […]
The Era of Personalized Cancer Therapeutics
Isabel Levy & Seema Bachoo Glossary Adoptive T cell transfer, Allosteric site, Clonal expansion, CRISPR-Cas9, DNA, DNA sequencing, EGFR, ‘Gain-of-function’ mutation, Genome, Genomic Instability, GTPase, GDP, GTP, Kinase, ‘Loss-of-function’ mutation, MAPK signaling pathway, Mutation, Oncogene/Proto-oncogene, Personalized Cancer Medicine, PI3K pathway, RAS, TP53 gene, Tumor suppressor gene Background Cancer: a disease of the genome […]
Human African trypanosomiasis (HAT): past to present and beyond
Aaron Logsdon Abbreviations BBB, Blood brain barrier; DDT, dichlorodiphenyltrichloroethane; DRC, the Democratic Republic of the Congo; HAT, Human African Trypanosomiasis; NECT, nifurtimox-eflornithine combination therapy; NTD, neglected tropical disease; ODC, ornithine decarboxylase; VSG, variant surface glycoprotein Glossary antigen, antigenic variation, arsenic, asymptomatic, clinical trial, dementia, drug, drug resistance, energy metabolism, endemic, epidemic, fever, host, […]
What is Digital Health and how is it revolutionizing healthcare?
Olivia Crossley Keywords Arrhythmia, Artificial intelligence, Blood Pressure, Consultant, Digital health, Electrodes, EEG, ECG, FDA, Machine Learning, Side effects, Telemedicine, Ultrasound, UK’s General Data Protection Regulation, Wearable technologies Digital technologies are electronic devices that analyze and store different kinds of information. These technologies have revolutionized how we communicate, learn, and shop. Now, digital devices […]
What is phage therapy and could it be used as an alternative to antibiotics?
Sam Jarada Glossary bactericidal, bacteriostatic, capsid, cell wall, DNA gyrase, dosage, dysentery, efficacy, enzyme, microbiome, lipid, lysis, lytic, nucleic acid, pathogenic, placebo, RNA, transcription, translation Introduction Phage therapy is a type of treatment that makes use of bacteriophages (phages), (a type of virus that only infect bacteria). Phages are composed of a nucleic […]
What is CAR-T cell therapy?
Seema Bachoo Immunotherapy is a type of cancer treatment that makes use of a patient’s own immune system to target and destroy cancer cells, with the aim of eliminating cancer from the body. There are several different types of immunotherapies. Cytokine-based immunotherapies harness the power of cytokines, which are soluble proteins that stimulate and […]
What is meant by the terms Personalized and Precision Medicine?
Lovisa Lindquist Glossary Cell Cycle, Chromosome, Cystic Fibrosis, CFTR gene, Deletion, DNA, Epigenetics, Frameshift Mutation, Gene, Gene Therapy, Genetic Testing, Genotype, Inversion, mRNA, Mutation, Personalized Medicine, Phenotype, Precision Medicine, Protein, Translocation, Tumour Heterogeneity, Tumor Suppressor Gene Currently, the majority of healthcare systems around the world employ a ‘one-size-fits-all’ approach when treating patients that have […]