Personalized & precision medicine approaches for the treatment of cardiovascular disease
Isabela Garcia Pleijlar Abbreviations CAD, Coronary Artery Disease; CHD, Congenital Heart Disease; CVD, Cardiovascular Disease; DNA, Deoxyribonucleic acid; ESCs, Embryonic Stem Cells; FDA, Food and Drug Administration; FRESH, Freeform Reversible Embedding of Suspended Hydrogels; hERG, the human ether-a-go-go related gene; hESC-CM, human Embryonic Stem Cell-derived Cardiomyocytes; HGF, Hepatocyte Growth Factor; hiPSC-CMs, human induced Pluripotent […]
Stem cell therapy as a potential treatment for breast cancer
Xuanqi Song Glossary Aromatase inhibitor, Astrocyte, Blastocyst, Chemotherapy, Ectoderm, Endoderm, Hematopoetic, Immunotherapy, in vitro, Lymphoma, Mesenchymal, Mesoderm, Molecular marker, Mutation, Pluripotent, Pluripotent, Quiescence, Somatic cell, Stem cell therapy Abbreviations Ais, Aromatase inhibitors; ASC, adult stem cell; CSC, cancer stem cell; ESC, embryonic stem cell; HER2, Human epidermal growth factor receptor 2; HR+, hormone receptor positive; […]
Advanced Therapies Congress 2023
ExCeL centre, London, 14-15 March, 2023 On the 14th and 15th of March 2023, PMM team members Atiyeh Razavi, Isabela Garcia Pleijlar, and Clotilde Vazquez attended the Advanced Therapies Congress held at the London ExCeL. The Advanced Therapies Congress explored, defined, and attempted to tackle the main challenges currently being faced when it comes […]
Glioblastoma: Current Therapies and Recent Therapeutic Advances
Eleanor Doherty Glossary Antibody, Antidepressant, Antigen, Apoptosis, Astrocyte, CAR-T Cell Therapy, Atypia, Clinical Trial, CNS, Dendritic Cell Vaccine, Epidermal Growth Factor, Ex-Vivo, Glioblastoma Multiforme, Glioma, Immunotherapy, Metastasis, Mitotic Activity, Monoclonal Antibody, Necrosis, Neuron, Neurotransmitter, Oncology, Oncolytic Virotherapy, Prognosis, Radiotherapy, Stem Cell, Surgical Resection, Tumor, Vaccine Therapy, Vascular Endothelial Growth Factor Abbreviations BBB, blood-brain […]
Advanced Therapies Europe 2022
On the 31st August and 1st September, 2022, PMM volunteer and team member, Rithika Ganesh, attended the annual Advanced Therapies Europe Conference which was held at the Royal Lancaster hotel in London, United Kingdom. The Advanced Therapies Europe 2022 conference focused on exploring the commercialization of advanced therapy medicinal products (ATMPs), with talks […]
What is phage therapy and could it be used as an alternative to antibiotics?
Sam Jarada Glossary bactericidal, bacteriostatic, capsid, cell wall, DNA gyrase, dosage, dysentery, efficacy, enzyme, microbiome, lipid, lysis, lytic, nucleic acid, pathogenic, placebo, RNA, transcription, translation Introduction Phage therapy is a type of treatment that makes use of bacteriophages (phages), (a type of virus that only infect bacteria). Phages are composed of a nucleic […]
Genomics: The Advent of Preventative Medicine?
Olivia Crossley Glossary Amniocentesis, Cell, Amyotrophic lateral sclerosis, Chorionic villus sampling, Chromosome, COVID-19, CRISPR-Cas9, Cystic fibrosis, DNA, Duchenne Muscular Dystrophy, Etiology, Familial Hypercholesterolemia, Gene, Genetic Counselling, Genetic Testing, Hemophilia, Leopard syndrome, Mucopolysaccharidosis type I, Noncoding DNA, Parkinson’s disease, Pharmacogenomics, Phenylketonuria, Precision Medicine, Prenatal testing, Severe Combined Immunodeficiency Disorder, Spinal Muscular Atrophy What is […]
COVID-19: How will testing and vaccines have to adapt to new variants?
Joana Vidigueira Glossary Antibody, Antigen, Antigen-presenting Cell, B cell, Booster, Clinical Trial, COVID-19, Dendritic Cell, Deoxyribonucleic Acid, Epidemiology, Helper T-cell, Host Cell, Immunity, Immune Response, Killer T-cell, Lymph Node, Macrophage, Mutation, Ribonucleic acid, RT-PCR, SARS-CoV-2, Vaccine, Variant, Virus Abbreviations SARS: Severe Acute Respiratory Syndrome, CoV: coronavirus, MERS: Middle Eastern Respiratory Syndrome, DNA: deoxyribonucleic acid, […]
What is CAR-T cell therapy?
Seema Bachoo Immunotherapy is a type of cancer treatment that makes use of a patient’s own immune system to target and destroy cancer cells, with the aim of eliminating cancer from the body. There are several different types of immunotherapies. Cytokine-based immunotherapies harness the power of cytokines, which are soluble proteins that stimulate and […]
Pharmacogenomics: The future of medicine?
Celeste Cohen Picture credit: National Human Genome Research Institute Note: All terms shown in bold are defined in the glossary at the end of the article. Defining Pharmacogenomics From chemotherapy to HIV drugs, the past century has seen rapid advances in medical innovation, which have given rise to a wide range […]