Advanced Therapies Congress 2024

ExCel Centre, London, 19-20 March, 2024   Day 1, 19th March 2024 13:20 – 13:40 Cell Therapy for Parkinson’s Disease – Seth Ettenberg Cell Therapy – Track 3, written by Esther How Parkinson’s disease (PD) is a neurodegenerative disorder that impacts millions of people worldwide. PD is the second most common neurodegenerative disorder after Alzheimer’s, […]

Surgical Robotics: The Future of Surgery?

Nicole Broughton   Glossary Benign prostatic hyperplasia, Biopsy, Bronchoscopy, Colorectal, Complication, COVID-19, Endometrial cancer, Gynecologic, Laparoscopy, Minimally invasive surgery, Musculoskeletal, Nosocomial infection, Oropharyngeal cancer, Pedicle screws, Prostatectomy, Quality of life, Robotic laparoscopic radical prostatectomy, Surgical Robotics, Thoracic, Tumor Abbreviations Benign prostatic hyperplasia, BPH; Lower urinary tract symptoms, LUTS; Minimally invasive surgery, MIS   Introduction In […]

Glioblastoma: Current Therapies and Recent Therapeutic Advances

Eleanor Doherty   Glossary Antibody, Antidepressant, Antigen, Apoptosis, Astrocyte, CAR-T Cell Therapy, Atypia, Clinical Trial, CNS, Dendritic Cell Vaccine, Epidermal Growth Factor, Ex-Vivo, Glioblastoma Multiforme, Glioma, Immunotherapy, Metastasis, Mitotic Activity, Monoclonal Antibody, Necrosis, Neuron, Neurotransmitter, Oncology, Oncolytic Virotherapy, Prognosis, Radiotherapy, Stem Cell, Surgical Resection, Tumor, Vaccine Therapy, Vascular Endothelial Growth Factor   Abbreviations BBB, blood-brain […]

Advanced Therapies Europe 2022

    On the 31st August and 1st September, 2022, PMM volunteer and team member, Rithika Ganesh, attended the annual Advanced Therapies Europe Conference which was held at the Royal Lancaster hotel in London, United Kingdom. The Advanced Therapies Europe 2022 conference focused on exploring the commercialization of advanced therapy medicinal products (ATMPs), with talks […]

What is phage therapy and could it be used as an alternative to antibiotics?

  Sam Jarada   Glossary bactericidal, bacteriostatic, capsid, cell wall, DNA gyrase, dosage, dysentery, efficacy, enzyme, microbiome, lipid, lysis, lytic, nucleic acid, pathogenic, placebo, RNA, transcription, translation Introduction Phage therapy is a type of treatment that makes use of bacteriophages (phages), (a type of virus that only infect bacteria). Phages are composed of a nucleic […]

Genomics: The Advent of Preventative Medicine?

Olivia Crossley   Glossary Amniocentesis, Cell, Amyotrophic lateral sclerosis,  Chorionic villus sampling,  Chromosome, COVID-19, CRISPR-Cas9,  Cystic fibrosis, DNA, Duchenne Muscular Dystrophy, Etiology, Familial Hypercholesterolemia, Gene, Genetic Counselling, Genetic Testing, Hemophilia, Leopard syndrome, Mucopolysaccharidosis type I,  Noncoding DNA, Parkinson’s disease, Pharmacogenomics, Phenylketonuria, Precision Medicine, Prenatal testing,  Severe Combined Immunodeficiency Disorder, Spinal Muscular Atrophy   What is […]

COVID-19: How will testing and vaccines have to adapt to new variants?

Joana Vidigueira   Glossary Antibody, Antigen, Antigen-presenting Cell, B cell, Booster, Clinical Trial, COVID-19, Dendritic Cell, Deoxyribonucleic Acid, Epidemiology, Helper T-cell, Host Cell, Immunity, Immune Response, Killer T-cell, Lymph Node, Macrophage, Mutation, Ribonucleic acid, RT-PCR, SARS-CoV-2, Vaccine, Variant, Virus Abbreviations SARS: Severe Acute Respiratory Syndrome, CoV: coronavirus, MERS: Middle Eastern Respiratory Syndrome, DNA: deoxyribonucleic acid, […]

What is CAR-T cell therapy?

Seema Bachoo   Immunotherapy is a type of cancer treatment that makes use of a patient’s own immune system to target and destroy cancer cells, with the aim of eliminating cancer from the body. There are several different types of immunotherapies. Cytokine-based immunotherapies harness the power of cytokines, which are soluble proteins that stimulate and […]

Pharmacogenomics: The future of medicine?

Celeste Cohen           Picture credit: National Human Genome Research Institute         Note: All terms shown in bold are defined in the glossary at the end of the article. Defining Pharmacogenomics From chemotherapy to HIV drugs, the past century has seen rapid advances in medical innovation, which have given rise to a wide range […]

How immunotherapy can improve colorectal cancer prognosis

Aaron Logsdon   Abbreviations CAR, chimeric antigen receptor; CAR-T, chimeric antigen receptor T lymphocyte therapy; CRC, colorectal cancer; DCR, disease control rate; dMMR, mismatch repair-deficient; FDA, US Food and Drug Administration; ICI, immune checkpoint inhibition; MMR, mismatch repair genes; MSI-H, high microsatellite instability; MSS, microsatellite stable; OR, objective response; pMMR, mismatch repair proficient; Treg, T […]