Prostate cancer research: Latest advances
Tala Elremmash Glossary: Brachytherapy, BRCA genes, Digital Rectal Examination (DRE), External Beam Radiation Therapy (EBRT), ExoDx Prostate (EPI), 68Ga-PSMA-11, Gleason Score, High Intensity Focused Ultrasound (HIFU), Intensity Modulated Radiation Therapy (IMRT), 4Kscore Test, Multiparametric Magnetic Resonance Imaging (mpMRI), PCA3, Prostatic Intraepithelial Neoplasia (PIN), Prostate-Specific Antigen (PSA), Prostate-specific Membrane Antigen Positron Emission Tomography (PSMA-PET), Stereotactic […]
Glioblastoma: Current Therapies and Recent Therapeutic Advances
Eleanor Doherty Glossary Antibody, Antidepressant, Antigen, Apoptosis, Astrocyte, CAR-T Cell Therapy, Atypia, Clinical Trial, CNS, Dendritic Cell Vaccine, Epidermal Growth Factor, Ex-Vivo, Glioblastoma Multiforme, Glioma, Immunotherapy, Metastasis, Mitotic Activity, Monoclonal Antibody, Necrosis, Neuron, Neurotransmitter, Oncology, Oncolytic Virotherapy, Prognosis, Radiotherapy, Stem Cell, Surgical Resection, Tumor, Vaccine Therapy, Vascular Endothelial Growth Factor Abbreviations BBB, blood-brain […]
The Era of Personalized Cancer Therapeutics
Isabel Levy & Seema Bachoo Glossary Adoptive T cell transfer, Allosteric site, Clonal expansion, CRISPR-Cas9, DNA, DNA sequencing, EGFR, ‘Gain-of-function’ mutation, Genome, Genomic Instability, GTPase, GDP, GTP, Kinase, ‘Loss-of-function’ mutation, MAPK signaling pathway, Mutation, Oncogene/Proto-oncogene, Personalized Cancer Medicine, PI3K pathway, RAS, TP53 gene, Tumor suppressor gene Background Cancer: a disease of the genome […]
Advanced Therapies Congress, 24-25 May, 2022, ExCel, London
On the 24th of May, 2022, PMM team members, Xuanqi Song and Sam Jarada, attended the Advanced Therapies Congress held at the London ExCeL. The Advanced Therapies Congress explored, defined, and attempted to tackle the main challenges currently being faced when it comes to the development of patient access to advanced therapy medicinal products (ATMP). […]
What is CAR-T cell therapy?
Seema Bachoo Immunotherapy is a type of cancer treatment that makes use of a patient’s own immune system to target and destroy cancer cells, with the aim of eliminating cancer from the body. There are several different types of immunotherapies. Cytokine-based immunotherapies harness the power of cytokines, which are soluble proteins that stimulate and […]
How immunotherapy can improve colorectal cancer prognosis
Aaron Logsdon Abbreviations CAR, chimeric antigen receptor; CAR-T, chimeric antigen receptor T lymphocyte therapy; CRC, colorectal cancer; DCR, disease control rate; dMMR, mismatch repair-deficient; FDA, US Food and Drug Administration; ICI, immune checkpoint inhibition; MMR, mismatch repair genes; MSI-H, high microsatellite instability; MSS, microsatellite stable; OR, objective response; pMMR, mismatch repair proficient; Treg, T […]