Biomarkers

Image credit: Cancer Research UK/ LRI EM Unit


Biological molecules found in blood, other body fluids, or tissues that are a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

For any unfamiliar terms, please visit:
https://www.merriam-webster.com/medical

This table is searchable and sortable. Just click on a company logo to go to the company website or on the ad/banner/video to see an enlarged view. Simply click outside the image to return to normal view. The first row shows what a complete listing would look like. Click here to find out how you can get a company listing.

To return to the table listing all of our Directories, click here.

How to search PMM Directories

Simply enter your search terms into the search box located at the top of each Directory and then click on the blue search icon to the right. Search terms could include the name of a medical condition, type of innovation/technology, or company name, or any terms related to the condition or innovation type that you are interested in. For example, you could enter a term such as ´app´, ´gene´, ´cancer´, ´dementia´, ´epidermolysis bullosa´, or ´Pfizer´. You can also sort each of the columns alphabetically simply by clicking on the arrows that will appear to the right of the column´s name when you hover the mouse on that cell.

OrganizationCountry InnovationCompany Info Ad/Banner/VideoCompany News
Personalize My MedicineUKPlatform for medical innovationPMM keeps you informed about the latest advancements in medical innovation with a focus on personalized and precision medicine approaches to healthcareScreenshot 2023-02-20 at 09.43.05Screenshot 2023-02-20 at 08.35.30Subscribe to PMM's free monthly newsletter here!
AbbvieUSBuilding and using their understanding of biomarkers in solid tumors to guide the development of immunotherapies, targeted small molecule inhibitors and antibody drug conjugates (ADCs)
AbiosciencesUSUsing single-cell genomics and bioinformatics to gain molecular insights into human diseases and translate them into effective therapeutics and diagnostics The first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
AcobiomFranceidentification of new biomarkers and in the development of innovative Diagnostics in Translational Research and Precision Medicine
Active MotifUSDeveloper of life science tools intended to bring epigenetics into the translational and precision medicine segments
AdesisUSCompounds developed for clients have found use in life-enhancing oncology, anti-infective, animal treatment, central nervous system, immunotherapy, therapeutic, ophthalmic, biomarkers, skin care, catalysts and other applications
Advanced Cell DiagnosticsUSdeveloping cell- and tissue-based research and diagnostic tests for personalized medicine
Akoya BiosciencesUScomprehensive single-cell imaging solutions that allow researchers to phenotype cells with spatial context and visualize how they organize and interact to influence disease progression and response to therapyThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Alto NeuroscienceUSartificial intelligence (AI)-enabled platform measures biomarkers like EEG and wearable data, behavioral patterns, genetics, and other factors to match patients with the treatment they are most likely to respond to
APIS Assay Technologies Ltd.UKBiomarker Industrial Research Programme. This structured R&D programme undertakes industrial research on biomarker-based diagnostic assays, targeting oncology, inflammatory, cardiovascular, infectious disease and inherited disease areas
Augurex Life Sciences Corp.Canadacommercialized blood test, the 14-3-3η Blood Test, can detect Rheumatoid Arthritis earlier, show treatment effectiveness, and reveal joint damage
Bill & Melinda Gates Medical Research Institute USdrugs, biologics, and vaccines
BioAgilytixUSservices for biomarker, immunogenicity, pharmacokinetics (PK), and cell-based assays and diagnostic testing servicesThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
BioArcticSwedenfocusing on disease modifying treatments and reliable biomarkers and diagnostics for neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease. The company is also developing a potential treatment for Complete Spinal Cord Injury
Biocare MedicalUSsupplier and developer of primary antibodies and automated immunohistochemistry (IHC) medical equipment for lab testing
Biocept Inc.USCNSide™ assay provides enhanced detection and analysis of tumor cells and cell-free DNA from cerebrospinal fluid (CSF)
BiocratesAustriametabolomics kits allow for the analysis of up to 630 metabolites across multiple analyte classes in a single run
Biodesix IncUSdiagnostic services for biopharma partners, including biomarker discovery, assay design and development, fit-for-purpose regulatory strategies, clinical trial testing, commercialization, and companion diagnostic capabilitiesThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
BioIVTUSprovider of high-quality biological specimens and value-added services, specializing in control and disease state samples including human and animal tissues, cell products, blood and other biofluids
Biological DynamicsUSproprietary Verita™ platform simplifies access to biomarkers, nanoparticles, and nucleic acids, enabling differentiated multiomic applications
BioSyntagmaUSMolecular Fingerprint™ (mPrint™) platform creates a comprehensive, multi-omic, and spatial profile of tissue to enhance understanding of patient’s cancer so they can be matched with relevant therapies to prevent acquired drug resistance. bioSyntagma’s mPrint™ platform for implementation of precision medicine for cancer treatment
CellCartaCanadaoffers access to integrated analytical platforms in immunology (immune monitoring), histopathology, proteomics and genomics, as well as digital pathology/AI and sample management, logistics and kitting services
Canopy BiosciencesUSproprietary platform ChipCytometry™ is an image-based high-plex proteomics instrument for spatial biology research that allows quantification of virtually unlimited protein biomarkers on a sample with true single-cell resolutionThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Centre for Human Drug ResistanceNetherlandsrange of high quality, data intensive clinical pharmacology services
Clarigent HealthUSClairity software unites vocal biomarkers with self-assessment scales and clinical judgment to generate individual progress trends, risk alerts, and population insights to mental healthcare providers
Coral Biotechnology Inc.USprovides contract research services for molecular analysis in addition to clinical trial and bio-marker investigation studies. The company also provides laboratory studies for gene expression analysis, genomics and epigenetics
CorDxUSrapid testing and point-of-care medical device solutions used in the detection of infectious disease such as COVID-19, pregnancy, drugs of abuse, biomarkers, and more
CytomX TherapeuticsUSDevelops cancer immunotherapies, drug conjugates (PDCs), T-cell engaging Probody bispecifics and ProCAR-NK cell therapies based on Protease-Activated Antibodies, 'Probodies'The first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Denali TherapeuticsUSDeveloping therapies to treat neurodegenerative diseases
Denovo BiopharmaUS industry's first platform and algorithm to perform de novo genomic biomarker discovery retrospectively using archived clinical samples. This technology is especially useful for late stage clinical drugs that have completed trials with unsatisfactory efficacy or side effects
Discovery Life Sciences UShighly characterized human biospecimens and cellular starting materials integrated with expert multi-omic analytical services to advance cell and gene therapy and precision medicine programs for cancer, infectious disease, and other complex conditions
Dyve BiosciencesUStransdermal platform allows us to formulate a broad range of molecules without compromising pharmacokinetics
Early is Good UStests to enable early, accurate, and widely accessible detection of renal system diseases, including bladder, kidney, and prostate cancers, by assessing specific biomarkers found in urineThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Engitix TherapeuticsUKusing their human extracellular matrix (ECM)-based discovery platform to develop a portfolio of programmes in fibrosis and solid tumours
Envol BiomedicalUSpreclinical and clinical pharmacology services for drug discovery, toxicology and early clinical trials in support of small molecules and biologics
Ethos BiosciencesUSproviding diagnostic tools for scientists and practitioners
Exosome DiagnosticsUSminimally invasive molecular diagnostics in blood and urine to enable doctors to select optimal therapies for cancer and other diseases
Firalis SwitzerlandDevelopment BM-based diagnostic, prognostic and theranostic tools: RUO Kits (Research-Use-Only), based on validated innovative biomarkers and IVD Tools (In Vitro Diagnostic), based on a combination of clinically qualified biomarkersThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Flagship BiosciencesUSspatial biology and biomarker services
FOXO TechnologiesUSoffers leading supervised machine learning and artificial intelligence technologies to identify epigenetic biomarkers that measure current states of health and aging
Fujirebio Diagnostics ABJapandeveloping new technologies and unique biomarkers with high clinical value
Gritstone BioUSdeveloping immunotherapies for cancers and infectious diseases
Ikena OncologyUSpipeline of programs focused on genetically defined or biomarker-driven cancers to target specific patient populationsThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
ImmunexpressUSSeptiCyte® quantifies the specific molecular biomarkers from a patient's immune system ('host response'​). Biomarkers capture signals from a patient's immune system in response to infection. These biomarkers may hold the key to early detection of sepsis, as well as guiding the use and timing of drugs and other therapies
ImmaticsGermanypipeline of Adoptive Cell Therapies and TCR Bispecifics as well as our partnerships with global leaders in the pharmaceutical industry
ImmunoviaSwedenTests based on antibody biomarker microarray analysis using advanced machine-learning and bioinformatics to single-out a set of relevant biomarkers that indicate a certain disease, thereby forming a unique “disease biomarker signature”
IROA TechnologiesUSdevelop metabolomic workflow tools that automate the measurement of biochemicals using internal standardsThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
IsoPlexisUSdevelops a single-cell detection system identifying patient immune response
IxicoUKneuroimaging and digital biomarker solutions and data analysis services
KCAS Bioanalytical & Biomarker ServicesUSbioanalytical, biomarker, cellular and molecular assay services and clinical kitting and storage management
Kiromic USproprietary DIAMOND® artificial intelligence (AI) platform to discover and develop cell and gene therapies with a therapeutic focus on immuno-oncology and other diseases. Kiromic is in the process of developing a multi-indication allogeneic CAR-T cell therapy that exploits the natural potency of Gamma Delta T-cells to target solid cancers
Known MedicineUSmachine learning-based sensitivity assay, paired with -omics data, allows identification of predictive biomarkers and the most likely responders for new drugsThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Kura OncologyUSpipeline includes tipifarnib, a farnesyl transferase inhibitor, currently in a registration-directed clinical trial and KO-539, a menin-MLL inhibitor, currently in a Phase 1/2A clinical trial
Laureate Institute for Brain ResearchUSdeveloping potential biomarkers (including genetic sampling, anatomical MRI, MRI spectroscopy, and functional magnetic resonance imaging (fMRI)) of patient groups defined by partitioning of clinical phenotypes to be added to the longitudinal clinical studies
Linus BioUSpipeline comprises precision exposome medicine biomarkers and target discovery across disease domains for which historically no molecular endpoints have been available in medical practice or for clinical trials, including CNS (autism spectrum disorder, amyotrophic lateral sclerosis), gastroenterology (inflammatory bowel disease), renal disease and oncology
MedQIA, LLCUSmultidisciplinary biomarker R&D program which is a collaborative effort encompassing imaging physics, computer vision, pattern classification, biostatistics, and radiological sciences
Meso Scale Diagnostics LLCUSMULTI ARRAY technology enhances medical research and drug development by enabling researchers to profile many biomarkers simultaneously in a single sample without compromising assay performanceThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Morphic TherapeuticUSOral integrin therapies for patients with immunological, fibrotic, neoplastic and vascular diseases
MPI ResearchUS strong presence within the cellular and molecular biology fields, biomarkers, and gene therapy
NeuropointDxUScompound safety screening division Stemina Biomarker Discovery used to develop metabolomics platform for identifying differences in metabolism in children with Autism Spectrum Disorder (ASD) and other neurological disorders
Nordic Bioscience A/SDenmark Their Protein Fingerprint technology is usedto identify fragments of the ECM that are released from affected tissues and develop blood-based biomarker assays to quantify disease activity with the aim of precision medicine
Olaris USleveraging metabolomics and machine learning for the discovery and development of its myOLARIS™ diagnostics products, which aim to optimize treatments and outcomes for individual patients. Metabolite diagnostics empower therapeutic selection, treatment effectiveness monitoring, disease diagnosis, and target identification across indications and therapeutics areas, including oncology, solid-organ transplant, and neurodegenerationThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Olink TherapeuticsSwedenhigh-multiplex technique to identify actionable biomarkers, with a strong focus on the human plasma proteome
OncoDNABelgiumprovides clinical guidance for the treatment and real-time monitoring of late stage cancer patients and supports research and drug development in cancer and genetic disease
OncorusUSIV-administered, self-amplifying RNA medicines for the treatment of cancer
Oryzon GenomicsSpaindevelopment of epigenetics-based therapeutics, with a strong focus on personalized medicine approaches to CNS disorders and oncology
Pax NeuroscienceUSdevelopment and commercialization of blood tests for depression diagnosis and for antidepressant response. These tests are based on novel protein biomarkers derived from hypothesis-driven data setsThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Pieris USAnticalin-based drugs to target validated disease pathways in a unique and transformative way. Pipeline includes immuno-oncology multi-specifics tailored for the tumor micro-environment, an inhaled Anticalin to treat uncontrolled asthma, and a half-life-optimized Anticalin to treat anemia
PrecisionLife UKGenerating understanding of the biology driving chronic diseases, stratifying patient populations to define new subgroups of patients
Proteomedix AGSwitzerlandNon-invasive diagnostic tests to detect and assess the prognosis of cancer, as well as to match patients with safer and more effective therapies. The first product is a blood-based test for the early diagnosis of prostate cancer
Pyxant LabsUSdirectly supporting research into cure for hepatitis, antiviral therapeutics for HIV, a fundamental understanding of Alzheimer’s Disease, antisense therapeutics, and therapeutics for COVID-19
RareCyteUSSpatial Biology and Liquid Biopsy solutionsThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
RenalytixUS proprietary solution that successfully enables early-stage, progression risk assessment for kidney health
REPROCELLJapanaccess to human tissues (BioServe) and human tissue testing (Biopta), in addition to stem cell culture media, reprogramming technologies, reagents, and iPSC-derived cell types (Stemgent)
Rules-Based Medicine a Q² Solutions CompanyUSbiomarker services and a novel whole blood immunophenotyping device (TruCulture®). RBM’s internally developed and manufactured immunoassays based on Multi-Analyte Profiling (MAP) and Single-Molecule Array (SimoaTM) ultrasensitive immunoassay technology
SapientUSplatform combines next-gen rapid liquid chromatography-mass spectrometry (rLC-MS) technologies – able to assay >11,000 small molecule biomarkers per biosample – computational learning, and an expansive proprietary Human Biology Database with data from several hundred thousand biosamples
SengenicsUSusing their patented KREX protein folding technology to discover autoantibody biomarker signature for drug response prediction, patient stratification, and development of companion diagnosticsThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Sutro BiopharmaUSnext-generation cancer therapeutics - antibody drug conjugates, bispecific antibodies and cytokine derivatives
Synexa Life SciencesNetherlands expertise in biomarker selection and panel design for each phase of clinical development
Tango TherapeuticsUSdeveloping novel medicines targeting cancer vulnerabilities to deliver transformational new therapies for patients
Target DiscoveryUSInnovative testing strategies leveragING the latest advances in analytical instrumentation, surface chemistry, microfluidics, nanotechnology, signal processing, and machine learning
Theta BiomarkersGreeceoffer comprehensive analysis of biological samples with 10+ validated protocols and 50+ fit for purpose methodsThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
TRON-MainzGermanyidentifying “omics”-based biomarkers and developing personalized therapies
QIBAUSadvancing quantitative imaging and the use of imaging biomarkers
Quant BiomarkersSwitzerlandusing artificial intelligence (AI) to develop personal biomarker panels for the targeted and early detection of chronic conditions to achieve a healthy lifespan
QuanterixUSdigitizing biomarker analysis with the goal of advancing the science of precision health
QuibimSpaindevelops quantitative biomarkers, companion diagnostics and other imaging tools for systems biology applications, from immuno-oncology to neurologyThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.
Scipher MedicineUS platform that identifies which drug will work based on the patient's fundamental disease biology, and not based on symptoms, disease classification, or medical bias
SingulexUS Singulex Clarity system is a fully-automated, in vitro diagnostics platform powered by Single Molecule Counting technology
TecanSwitzerlandproducts for application in agriculture, forensic solutions, analytical chemistry, cell biology, drug discovery, genomic solutions, protein science solutions, ELISA solutions, and synthetic biology. Its systems and components are used widely in clinical diagnostics and basic and translational research
UltivueUSDeveloping products and services using spatial phenomics that utilize emerging knowledge of human biology and enable the data-driven development of personalized cancer therapies
Wren TherapeuticsUKdrug discovery and development for protein misfolding diseases. Developing a broad pipeline of small molecule and antibody therapeutics, as well as diagnostics, spanning neurology, ophthalmology, and metabolic diseasesThe first row shows what your upgraded listing would look like. Click here to find out how you can upgrade your company's listing.